- Heart health: Can help maintain homocysteine levels already within normal range for cardiovascular wellness
- Methyl donor function: Provides three methyl groups per molecule to promote optimal cellular processes
- Liver function: Encouraging optimal liver health & bile production
- Blood pressure: Can support already normal blood pressure levels
- Mitochondrial health: Promoting cellular energy production & metabolic function
- Inflammatory response: Supporting balanced inflammatory processes throughout the body
TMG (trimethylglycine), also known as glycine betaine, delivers 500 mg per serving of this heart-healthy amino acid compound discovered in the 1950s.
Health benefits overview:
Are you concerned about maintaining optimal cardiovascular wellness?
Trimethylglycine (TMG), also known as glycine betaine, refers to three methyl groups attached to each molecule of glycine. When a TMG methyl group is donated to a molecule of homocysteine, it becomes methionine, a beneficial amino acid. While working to promote balanced homocysteine levels, alone or in conjunction with other nutrients, TMG has been recognized as an important nutrient for cardiovascular health.
Why it works:
TMG has been linked to heart wellness by encouraging already-normal homocysteine levels to promote optimal cardiovascular function. By having a positive impact on your homocysteine levels, TMG can help you stay vital by promoting multiple systems throughout your body.
TMG has also been associated with normal blood pressure and mitochondrial function. Moreover, it has been found to encourage liver wellness.
What makes homocysteine management so important for your health?
The role of TMG in balanced homocysteine metabolism is especially important when B vitamin levels are low. Some evidence suggests TMG may be more efficient at regulating homocysteine levels than folate, confirming its status as a crucial nutrient for cardiovascular and overall wellness.
Backed by science:
TMG as a methyl donor for cardiovascular support
Why has TMG been valued since the 1950s?
In the 1950s, TMG was discovered to be beneficial to the heart and it functions in a similar way as some B vitamins (B6, B12, and folate). Like B vitamins, TMG is a methyl donor, providing extra methyl groups to hasten the conversion of homocysteine back to methionine. When a TMG methyl group is donated to a molecule of homocysteine, it converts it to the non-toxic amino acid methionine.
Supporting balanced inflammatory response
Studies show TMG can encourage a balanced inflammatory response by inhibiting the expression of inflammatory proteins, which may partially explain its positive impacts throughout your body.
Dietary sources and gut microbiome interaction
Wheat bran is the main dietary source of TMG, with smaller amounts available in other cereal grains. TMG can also be made in your body from choline, an essential nutrient found in eggs, soybeans, and many other foods. Because intestinal microbes can make various by-products from TMG, the health of the gut microbiome influences the effects of TMG in the body.
How to take:
Please follow the dosage guidelines outlined in the Supplement facts or consult your healthcare practitioner for recommendations.
Amino Acids
Glycine
